![]() Participants were asked to complete questionnaires annually from 1996 to 2001, and then biennially through 2007. Approximately 68% of the invited female participants (n=9 039) returned completed questionnaires, thereby assenting to participate in the cohort study. Participants were 9 to 14 years old at enrollment in 1996. They are the offspring of women participating in the ongoing Nurses’ Health Study II (NHSII), a cohort study of over 116 000 female registered nurses. SubjectsParticipants are members of the Growing Up Today Study (GUTS), an ongoing cohort study of adolescents throughout the United States that was established in 1996.
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